https://www.longevitymagazine.co.uk/ An independent review journal on healthspan, preventative medicine and ageing. Eight graded claims from A to D, a published grading methodology, and evidence described qualitatively rather than quoted. No medical advice and nothing for sale. en-GB Sun, 09 Aug 2026 15:31:51 +0000 Northbank Media 2026 Northbank Media editorial@longevitymagazine.co.uk (Northbank Media) https://www.longevitymagazine.co.uk/the-future-of-longevity-revolutionary-anti-ageing-innovations-transforming-healthcare https://www.longevitymagazine.co.uk/the-future-of-longevity-revolutionary-anti-ageing-innovations-transforming-healthcare Fri, 31 Jul 2026 09:00:00 +0000 Senolytics, partial reprogramming, regenerative injectables, exosome-derived preparations and machine learning applied to ageing. What each field has actually shown, what it has not, and how far any of it is from clinical use. Longevity Magazine https://www.longevitymagazine.co.uk/the-complete-guide-to-modern-aesthetic-medicine https://www.longevitymagazine.co.uk/the-complete-guide-to-modern-aesthetic-medicine Fri, 31 Jul 2026 09:00:00 +0000 What contemporary aesthetic medicine consists of, how the main treatment families work, what the evidence supports, how the United Kingdom regulates it, and what a patient should establish before agreeing to anything. Longevity Magazine https://www.longevitymagazine.co.uk/the-aesthetic-clinic-evolution-why-branding-design-and-digital-experience-now-define-clinical-success https://www.longevitymagazine.co.uk/the-aesthetic-clinic-evolution-why-branding-design-and-digital-experience-now-define-clinical-success Fri, 31 Jul 2026 09:00:00 +0000 The clinical content of aesthetic medicine has changed less than the market around it. An analysis of why presentation, digital experience and operational design now decide which competent clinics survive, and what a patient should read into any of it. Longevity Magazine https://www.longevitymagazine.co.uk/reviews/vo2max-as-a-longevity-marker https://www.longevitymagazine.co.uk/reviews/vo2max-as-a-longevity-marker Fri, 31 Jul 2026 09:00:00 +0000 A graded review of cardiorespiratory fitness as a predictor of mortality. The prognostic claim is the strongest in this journal. The interventional claim is a separate and weaker one. Longevity Magazine https://www.longevitymagazine.co.uk/reviews/time-restricted-eating https://www.longevitymagazine.co.uk/reviews/time-restricted-eating Fri, 31 Jul 2026 09:00:00 +0000 A graded review of eating windows. Plenty of randomised human trials, mostly short, and a persistent difficulty separating the timing from the calories. Longevity Magazine https://www.longevitymagazine.co.uk/reviews/sleep-architecture-and-ageing https://www.longevitymagazine.co.uk/reviews/sleep-architecture-and-ageing Fri, 31 Jul 2026 09:00:00 +0000 A graded review of how sleep changes with age and what that means for health. Real measured changes, a U-shaped mortality association that is hard to interpret, and treatment trials that have disappointed. Longevity Magazine https://www.longevitymagazine.co.uk/reviews/senolytics-current-state https://www.longevitymagazine.co.uk/reviews/senolytics-current-state Fri, 31 Jul 2026 09:00:00 +0000 A graded review of senolytics. A compelling cellular hypothesis, striking animal results and human trials that remain small, short and early. Evidence grade D. Longevity Magazine https://www.longevitymagazine.co.uk/reviews/resistance-training-and-mortality https://www.longevitymagazine.co.uk/reviews/resistance-training-and-mortality Fri, 31 Jul 2026 09:00:00 +0000 A graded review of muscle-strengthening activity and survival. Consistent cohort evidence with self-reported exposure, and randomised evidence that stops at function rather than mortality. Longevity Magazine https://www.longevitymagazine.co.uk/reviews/rapamycin-and-mtor https://www.longevitymagazine.co.uk/reviews/rapamycin-and-mtor Fri, 31 Jul 2026 09:00:00 +0000 A graded review of rapamycin. The strongest preclinical lifespan evidence of any compound, and human evidence that stops well short of the claim. Evidence grade D, with an unusually clear path upward. Longevity Magazine https://www.longevitymagazine.co.uk/reviews/nad-precursors-nmn-and-nr https://www.longevitymagazine.co.uk/reviews/nad-precursors-nmn-and-nr Fri, 31 Jul 2026 09:00:00 +0000 A graded review of NMN and NR. The biochemistry is solid, the human trials are short and mostly measure blood metabolites rather than health. Evidence grade D, and what would move it. Longevity Magazine https://www.longevitymagazine.co.uk/reviews/metformin-for-healthspan https://www.longevitymagazine.co.uk/reviews/metformin-for-healthspan Fri, 31 Jul 2026 09:00:00 +0000 A graded review of metformin as an ageing intervention. Decades of safety data in diabetes, a large observational literature, and no completed trial testing the ageing claim itself. Evidence grade C. Longevity Magazine https://www.longevitymagazine.co.uk/longevity-and-aesthetics-the-future-of-ageing-well-in-london https://www.longevitymagazine.co.uk/longevity-and-aesthetics-the-future-of-ageing-well-in-london Fri, 31 Jul 2026 09:00:00 +0000 London has become the densest market in the United Kingdom for both longevity services and aesthetic medicine. An analysis of where the two fields genuinely overlap, where the overlap is marketing, and what actually predicts ageing well. Longevity Magazine https://www.longevitymagazine.co.uk/grading https://www.longevitymagazine.co.uk/grading Fri, 31 Jul 2026 09:00:00 +0000 The evidence grading methodology used throughout Longevity Magazine. Four bands from A to D, two claim types, the rules that cap a grade, and how grades change. Longevity Magazine https://www.longevitymagazine.co.uk/explainers/surrogate-endpoints-and-why-they-mislead https://www.longevitymagazine.co.uk/explainers/surrogate-endpoints-and-why-they-mislead Fri, 31 Jul 2026 09:00:00 +0000 Why a treatment that moves a biomarker so often fails to help anyone, what makes a surrogate valid, and how to spot the substitution when it happens. Longevity Magazine https://www.longevitymagazine.co.uk/explainers/supplement-regulation-in-the-uk https://www.longevitymagazine.co.uk/explainers/supplement-regulation-in-the-uk Fri, 31 Jul 2026 09:00:00 +0000 What being on sale in Britain actually certifies, the line between a food supplement and a medicine, how health claims are policed, and why efficacy is never assessed before sale. Longevity Magazine https://www.longevitymagazine.co.uk/explainers/how-to-read-a-clinical-trial https://www.longevitymagazine.co.uk/explainers/how-to-read-a-clinical-trial Fri, 31 Jul 2026 09:00:00 +0000 A working method for reading a trial report: the question asked, the design, the pre-registered endpoint, who was excluded, and the funding statement. Written for readers without a research background. Longevity Magazine https://www.longevitymagazine.co.uk/explainers/biological-age-tests-what-they-measure https://www.longevitymagazine.co.uk/explainers/biological-age-tests-what-they-measure Fri, 31 Jul 2026 09:00:00 +0000 What an epigenetic clock is trained on, why two tests disagree, why the same sample can give different answers on different days, and what a biological age result can and cannot support. Longevity Magazine https://www.longevitymagazine.co.uk/editorial-policy https://www.longevitymagazine.co.uk/editorial-policy Fri, 31 Jul 2026 09:00:00 +0000 The editorial policy of Longevity Magazine: funding and independence, how evidence is described, why there is no medical advice, corrections, and how the site is written for machine readers. Longevity Magazine https://www.longevitymagazine.co.uk/contact https://www.longevitymagazine.co.uk/contact Fri, 31 Jul 2026 09:00:00 +0000 Contact Longevity Magazine with a correction, with evidence we appear to have missed, or to suggest a claim for review. We answer no questions about individual health. Longevity Magazine https://www.longevitymagazine.co.uk/about https://www.longevitymagazine.co.uk/about Fri, 31 Jul 2026 09:00:00 +0000 Longevity Magazine is an independent review journal covering healthspan, preventative medicine and ageing. What it publishes, how it writes about evidence, and what it refuses to do. Longevity Magazine